Age-related neurodegeneration is characterized by the aggregation of a small number of proteins, including α-synuclein, that can become altered in a manner that encourages other molecules of the same protein to alter in the same way. These altered forms of protein precipitate to form structures solid fibrils and deposits, surrounded by a halo of toxic biochemistry that impairs cell function. Today’s open access paper explores just one of the ways in which α-synuclein harms cells, in this case by downregulating the operation of autophagy.
Autophagy is the name given to a collection of cellular maintenance processes that are particularly important in long-lived cells such as the neurons of the <a href="https://en.wikipedia.org/wiki/Central_nerv…
Age-related neurodegeneration is characterized by the aggregation of a small number of proteins, including α-synuclein, that can become altered in a manner that encourages other molecules of the same protein to alter in the same way. These altered forms of protein precipitate to form structures solid fibrils and deposits, surrounded by a halo of toxic biochemistry that impairs cell function. Today’s open access paper explores just one of the ways in which α-synuclein harms cells, in this case by downregulating the operation of autophagy.
Autophagy is the name given to a collection of cellular maintenance processes that are particularly important in long-lived cells such as the neurons of the <a href="https://en.wikipedia.org/wiki/Central_nerv…
The Lancet Psychiatry has published a new paper highlighting an urgent need to tackle the harmful impacts of the COVID-19 pandemic on mental health and potentially the brain. It warns that the pandemic could have a ‘profound’ and ‘pervasive impact’ on global mental health now and in the future, yet only a very small proportion of new scientific
The Lancet Psychiatry has published a new paper highlighting an urgent need to tackle the harmful impacts of the COVID-19 pandemic on mental health and potentially the brain. It warns that the pandemic could have a ‘profound’ and ‘pervasive impact’ on global mental health now and in the future, yet only a very small proportion of new scientific
We love Star Wars around these parts (our site is literally called “Nerd Fitness”), so you’re in the perfect place to begin your training, my young Padawan.
We specialize in creating nerdy themed workouts and today one of our coaches will walk you through an exercise routine that would make even Mace Windu proud.
We love Star Wars around these parts (our site is literally called “Nerd Fitness”), so you’re in the perfect place to begin your training, my young Padawan.
We specialize in creating nerdy themed workouts and today one of our coaches will walk you through an exercise routine that would make even Mace Windu proud.
IHRSA partners with over 100 trade organizations, representing over 30 U.S. business sectors, and 58 million American workers, to advocate for a Federal Direct Assistance Fund…
IHRSA partners with over 100 trade organizations, representing over 30 U.S. business sectors, and 58 million American workers, to advocate for a Federal Direct Assistance Fund…
Yale researchers will begin a clinical trial at Yale-New Haven Hospital to test the effectiveness of a drug called ibudilast (MN-166) for treating acute respiratory distress syndrome (ARDS), a life-threatening lung condition developed by some of the most seriously ill COVID-19 patients. The researchers are part of Yale’s Advanced Therapies Group, which was formed in
Yale researchers will begin a clinical trial at Yale-New Haven Hospital to test the effectiveness of a drug called ibudilast (MN-166) for treating acute respiratory distress syndrome (ARDS), a life-threatening lung condition developed by some of the most seriously ill COVID-19 patients. The researchers are part of Yale’s Advanced Therapies Group, which was formed in
In addition to delivering surprise doughnut packages, we opened our first drive-thru in Manchester on 16th April. The drive-thru is serving NHS, Police and Fire workers, who will be eligible to receive complimentary hot drinks and one of our three-packs of original glazed doughnuts. We hope to have all nine of our drive-thrus opened by the 27th April, to serve NHS, Police and Fire workers, to support them in the battle against COVID-19.
In addition to delivering surprise doughnut packages, we opened our first drive-thru in Manchester on 16th April. The drive-thru is serving NHS, Police and Fire workers, who will be eligible to receive complimentary hot drinks and one of our three-packs of original glazed doughnuts. We hope to have all nine of our drive-thrus opened by the 27th April, to serve NHS, Police and Fire workers, to support them in the battle against COVID-19.
by Women’s Brain Health Initiative: Thanks to the ongoing support of our partner Brain Canada, Women’s Brain Health Initiative’s newest edition of MIND OVER MATTER has just been published. Loaded with interesting science-based articles, MIND OVER MATTER brings you the latest research……
by Women’s Brain Health Initiative: Thanks to the ongoing support of our partner Brain Canada, Women’s Brain Health Initiative’s newest edition of MIND OVER MATTER has just been published. Loaded with interesting science-based articles, MIND OVER MATTER brings you the latest research……
by Women’s Brain Health Initiative: Your risk of developing dementia is influenced by a combination of genetic, environmental, and lifestyle factors. While there is nothing you can do about the genetics that you are born with, and there are only……
by Women’s Brain Health Initiative: Your risk of developing dementia is influenced by a combination of genetic, environmental, and lifestyle factors. While there is nothing you can do about the genetics that you are born with, and there are only……
“Life isn’t always fair. Some people are born into better environments. Some people have better genetics. Some are in the right place at the right time. If you’re trying to change your life, all of this is irrelevant. All that matters is that you accept where you are, figure out where you want to be, and then do what you can, today and every day, to hold your head high and keep moving forward.” ~Lori Deschene
Like millions of people these days, I have lost my job. But unlike millions of people, I’ve now lost the same job twice within a year. Which, strangely, makes me feel somewhat prepared for it. And that’s why I’d like to share with you how I dealt with the situation then, and how I’m dealing with it now. …
“Life isn’t always fair. Some people are born into better environments. Some people have better genetics. Some are in the right place at the right time. If you’re trying to change your life, all of this is irrelevant. All that matters is that you accept where you are, figure out where you want to be, and then do what you can, today and every day, to hold your head high and keep moving forward.” ~Lori Deschene
Like millions of people these days, I have lost my job. But unlike millions of people, I’ve now lost the same job twice within a year. Which, strangely, makes me feel somewhat prepared for it. And that’s why I’d like to share with you how I dealt with the situation then, and how I’m dealing with it now. …
