Source https://www.fightaging.org/archives/2023/08/extracellular-vesicles-from-young-cardiac-progenitor-cells-produce-benefits-in-old-mice/
The signaling environment in the body is generated by cells, communication mediated by the molecules that cells release and take up, many of which are packaged into extracellular vesicles. This signaling changes profoundly between development and adult life, and then again in important ways with advancing age. In principle, providing aged tissues with the signals passed back and forth during embryonic development will spur greater maintenance and regeneration. In practice, tissues are systems of great and only partially understood complexity, and attempts to beneficially manipulate signaling in this way are still very much a work in progress, even after decades of effort.
The transplantation of forms of stem cell is perhaps the most successful approach to date when it comes to manipulation of cell signaling for benefit. Stem cells …
Source https://www.fightaging.org/archives/2023/08/extracellular-vesicles-from-young-cardiac-progenitor-cells-produce-benefits-in-old-mice/
The signaling environment in the body is generated by cells, communication mediated by the molecules that cells release and take up, many of which are packaged into extracellular vesicles. This signaling changes profoundly between development and adult life, and then again in important ways with advancing age. In principle, providing aged tissues with the signals passed back and forth during embryonic development will spur greater maintenance and regeneration. In practice, tissues are systems of great and only partially understood complexity, and attempts to beneficially manipulate signaling in this way are still very much a work in progress, even after decades of effort.
The transplantation of forms of stem cell is perhaps the most successful approach to date when it comes to manipulation of cell signaling for benefit. Stem cells …
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