Source https://www.fightaging.org/archives/2022/10/in-health-and-mortality-do-human-genetic-variants-matter-more-with-age-or-less-with-age/
To what degree do genetic variants drive the observed differences in human life expectancy? The old consensus guesstimate was that environment determines 75% of life expectancy, and genetic variants the other 25%. Further, it is the common wisdom that gene variants become more important to life expectancy in later life, either by providing greater resilience to specific forms of damage and dysfunction, or slowing the pace at which that damage and dysfunction accumulates. A great deal of medical research is based on the insight that gene variants are thought to provide on disease processes.
Views on genetic variants are changing, however. Modern research that makes use of genetic databases that cover very large populations is trending in the direction of demonstrating that <a href="https://www.fightaging.org/archives/2019/08/the-genetics-of-human-longevity-in-a-nutshell-only-a-few-identified-variants-and-ever…
Source https://www.fightaging.org/archives/2022/10/in-health-and-mortality-do-human-genetic-variants-matter-more-with-age-or-less-with-age/
To what degree do genetic variants drive the observed differences in human life expectancy? The old consensus guesstimate was that environment determines 75% of life expectancy, and genetic variants the other 25%. Further, it is the common wisdom that gene variants become more important to life expectancy in later life, either by providing greater resilience to specific forms of damage and dysfunction, or slowing the pace at which that damage and dysfunction accumulates. A great deal of medical research is based on the insight that gene variants are thought to provide on disease processes.
Views on genetic variants are changing, however. Modern research that makes use of genetic databases that cover very large populations is trending in the direction of demonstrating that <a href="https://www.fightaging.org/archives/2019/08/the-genetics-of-human-longevity-in-a-nutshell-only-a-few-identified-variants-and-ever…
What Do You Think?
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