Investigating the Role of Microglia in Zebrafish Neural Regeneration

Source https://www.fightaging.org/archives/2022/12/investigating-the-role-of-microglia-in-zebrafish-neural-regeneration/

Some species, such as salamanders and zebrafish, exhibit proficient regeneration, in that individuals are capable of regrowing lost tissue in organs and limbs and central nervous system without scarring. In adult mammals, the result of injury is scarring rather than regrowth, even though embryos are capable of both initial growth and later complete regeneration. Following the hypothesis that mechanisms of proficient regeneration do in fact exist in adult mammals, but are in some way silenced, the research community is engaged in trying to identify the specific differences between mammals and highly regenerative species that determine whether regrowth or scarring takes place following injury.

One of the more interesting discoveries of recent years is that <a href="https://www.fightaging.org/arch…

Source https://www.fightaging.org/archives/2022/12/investigating-the-role-of-microglia-in-zebrafish-neural-regeneration/

Some species, such as salamanders and zebrafish, exhibit proficient regeneration, in that individuals are capable of regrowing lost tissue in organs and limbs and central nervous system without scarring. In adult mammals, the result of injury is scarring rather than regrowth, even though embryos are capable of both initial growth and later complete regeneration. Following the hypothesis that mechanisms of proficient regeneration do in fact exist in adult mammals, but are in some way silenced, the research community is engaged in trying to identify the specific differences between mammals and highly regenerative species that determine whether regrowth or scarring takes place following injury.

One of the more interesting discoveries of recent years is that <a href="https://www.fightaging.org/arch…

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