Source https://www.fightaging.org/archives/2022/04/mcl-1-inhibitors-as-a-novel-class-of-senolytic/
Researchers working with prostate cancer cells here show that senescent cancer cells depend upon Mcl-1 to prevent programmed cell death, a novel target with existing drugs that may prove useful as general purpose senolytics, able to clear senescent cells from tissues. Cancers are highly varied, and this would have to be tested against the more usual types of senescent cell present in the aged body. Even if only applicable in the context of some cancers, however, this is still a useful discovery. Cancer survivors have <a href="https://www.fightaging.org/archives/2016/06/undergoing-chemotherapy-or-radiotherapy-is-literally-a-damaging-experience-but-are-these-consequences-a-form-of-accelerated-ag…
Source https://www.fightaging.org/archives/2022/04/mcl-1-inhibitors-as-a-novel-class-of-senolytic/
Researchers working with prostate cancer cells here show that senescent cancer cells depend upon Mcl-1 to prevent programmed cell death, a novel target with existing drugs that may prove useful as general purpose senolytics, able to clear senescent cells from tissues. Cancers are highly varied, and this would have to be tested against the more usual types of senescent cell present in the aged body. Even if only applicable in the context of some cancers, however, this is still a useful discovery. Cancer survivors have <a href="https://www.fightaging.org/archives/2016/06/undergoing-chemotherapy-or-radiotherapy-is-literally-a-damaging-experience-but-are-these-consequences-a-form-of-accelerated-ag…
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