Reviewing the Mechanisms of Alzheimer's Disease

Source https://www.fightaging.org/archives/2020/07/reviewing-the-mechanisms-of-alzheimers-disease/

The present understanding of Alzheimer’s disease is illustrative of a broader issue with aging in general, in that while there is considerable evidence to pin down specific pathological mechanisms in cells and tissues, it is hard to prove exactly how these mechanisms interact. What is cause, what is consequence. What is important, what is merely a side-effect of other, important processes. At present there is some upheaval in the Alzheimer’s research community based on the failure of amyloid-β clearance to produce meaningful benefits in patients. This may or may not disrupt the present thinking on the condition, that early <a href="https://en.wikipedia.org/wiki/Amy…

Source https://www.fightaging.org/archives/2020/07/reviewing-the-mechanisms-of-alzheimers-disease/

The present understanding of Alzheimer’s disease is illustrative of a broader issue with aging in general, in that while there is considerable evidence to pin down specific pathological mechanisms in cells and tissues, it is hard to prove exactly how these mechanisms interact. What is cause, what is consequence. What is important, what is merely a side-effect of other, important processes. At present there is some upheaval in the Alzheimer’s research community based on the failure of amyloid-β clearance to produce meaningful benefits in patients. This may or may not disrupt the present thinking on the condition, that early <a href="https://en.wikipedia.org/wiki/Amy…

Flu and Pneumonia Vaccinations Tied to Lower Risk of Alzheimer’s

Source: http://www.brainhealtheducation.org/flu-and-pneumonia-vaccinations-tied-to-lower-risk-of-alzheimers/

Flu (influenza) and pneumonia vaccinations are associated with reduced risk of Alzheimer’s disease, according to new research reported at the Alzheimer’s Association International Conference 2020. Being vaccinated against influenza was associated with a 17% reduction in Alzheimer’s incidence. Pneumonia vaccinations given between the ages of 65 and 75, reduced Alzheimer’s risk by up to 40%.

Read More…

Source: http://www.brainhealtheducation.org/flu-and-pneumonia-vaccinations-tied-to-lower-risk-of-alzheimers/

Flu (influenza) and pneumonia vaccinations are associated with reduced risk of Alzheimer’s disease, according to new research reported at the Alzheimer’s Association International Conference 2020. Being vaccinated against influenza was associated with a 17% reduction in Alzheimer’s incidence. Pneumonia vaccinations given between the ages of 65 and 75, reduced Alzheimer’s risk by up to 40%.

Read More…

Combining Therapies as the Next Frontier for the Treatment of Aging

Source https://www.fightaging.org/archives/2020/07/combining-therapies-as-the-next-frontier-for-the-treatment-of-aging/

There are two activities in medical science in which both the academic research community and clinical development industry are truly terrible at achieving results, or indeed even at getting started at all. The first is transfer of programs from academia to industry. The renowned valley of death in the development of new medical biotechnologies is very real; so very many programs languish undeveloped simply because neither side can effectively coordinate with the other. The second is the testing of synergies between multiple therapies that are applied at the same time to the same patient for the treatment of the same condition. We live in a world in which age-related conditions are the result of multiple distinct contributing mechanisms, so why is it that the exploration and application of combined therapies targeting separate mechanisms is such a rare occurrence?

<p…

Source https://www.fightaging.org/archives/2020/07/combining-therapies-as-the-next-frontier-for-the-treatment-of-aging/

There are two activities in medical science in which both the academic research community and clinical development industry are truly terrible at achieving results, or indeed even at getting started at all. The first is transfer of programs from academia to industry. The renowned valley of death in the development of new medical biotechnologies is very real; so very many programs languish undeveloped simply because neither side can effectively coordinate with the other. The second is the testing of synergies between multiple therapies that are applied at the same time to the same patient for the treatment of the same condition. We live in a world in which age-related conditions are the result of multiple distinct contributing mechanisms, so why is it that the exploration and application of combined therapies targeting separate mechanisms is such a rare occurrence?

<p…

The Power of Compassion: How to Make Do in an Unfair World

Source http://feedproxy.google.com/~r/tinybuddha/~3/oAglpG9GcSM/

“A good head and good heart are always a formidable combination. But when you add to that a literate tongue or pen, then you have something very special.” ~Nelson Mandela

Ever thought, “Life is so unfair!”

Is it, really?

Has life given you circumstances that keep you in a deep, dark hole of disadvantages that seem impossible to clamber out of?

Has life decided that you need to live in abject poverty and watch everyone in your life suffer from being denied everything a human needs to be human?

Has life put you in a position where you wouldn’t dare to dream of something better, for yourself, for your family, about anything, ever?

My story is specifically about my home, Cape Town, South Africa.

A place so breathtaking, it reminds you cons…

Source http://feedproxy.google.com/~r/tinybuddha/~3/oAglpG9GcSM/

“A good head and good heart are always a formidable combination. But when you add to that a literate tongue or pen, then you have something very special.” ~Nelson Mandela

Ever thought, “Life is so unfair!”

Is it, really?

Has life given you circumstances that keep you in a deep, dark hole of disadvantages that seem impossible to clamber out of?

Has life decided that you need to live in abject poverty and watch everyone in your life suffer from being denied everything a human needs to be human?

Has life put you in a position where you wouldn’t dare to dream of something better, for yourself, for your family, about anything, ever?

My story is specifically about my home, Cape Town, South Africa.

A place so breathtaking, it reminds you cons…

“Let’s Ask Marion” is coming September 1!

Source https://www.foodpolitics.com/2020/07/progress-report-lets-ask-marion/

I just got the first copies of my forthcoming book with Kerry Trueman, Let’s Ask Marion: What You Need to Know about the Politics of Food, Nutrition, and Health.

The publication date was supposed to be September 29 but University of California Press moved it up to September 1.  The y will also publish the e-book on September 1.

This means it can be used in fall classes (I’m using it in the NYU undergraduate class I’m teaching on Food Politics in the Covid-19 Era.

Information about the book and its Table of Contents are here.

You can read the Introduction here.

And UC Press sent me these photos.

<…

Source https://www.foodpolitics.com/2020/07/progress-report-lets-ask-marion/

I just got the first copies of my forthcoming book with Kerry Trueman, Let’s Ask Marion: What You Need to Know about the Politics of Food, Nutrition, and Health.

The publication date was supposed to be September 29 but University of California Press moved it up to September 1.  The y will also publish the e-book on September 1.

This means it can be used in fall classes (I’m using it in the NYU undergraduate class I’m teaching on Food Politics in the Covid-19 Era.

Information about the book and its Table of Contents are here.

You can read the Introduction here.

And UC Press sent me these photos.

<…

7 Tips to Fix Knee Pain from Single-Leg Exercises

Source https://www.niashanks.com/knee-pain-single-leg-exercises/

tips to fix knee pain with single-leg exercises

You can listen to this article. Use the player below, download the MP3, or use iTunes.

“I can’t do single-leg exercises because they hurt my knees.”

If you’ve ever said that about a single-leg exercise, or all single-leg exercises, you’re not alone. Many trainees lament the sight of single-leg exercises in their workouts because they experience knee pain when doing them.

The good news is that you can often eliminate pain or discomfort by making a few adjustments to the workout or…

Source https://www.niashanks.com/knee-pain-single-leg-exercises/

tips to fix knee pain with single-leg exercises

You can listen to this article. Use the player below, download the MP3, or use iTunes.

“I can’t do single-leg exercises because they hurt my knees.”

If you’ve ever said that about a single-leg exercise, or all single-leg exercises, you’re not alone. Many trainees lament the sight of single-leg exercises in their workouts because they experience knee pain when doing them.

The good news is that you can often eliminate pain or discomfort by making a few adjustments to the workout or…

Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (AD)

Source: https://sharpbrains.com/blog/2020/07/27/systematic-review-finds-ten-lifestyle-factors-that-clearly-impact-the-probability-of-developing-alzheimers-disease-ad/

Although there’s still no cure, researchers are continuing to develop a better understanding of what increases a person’s risk of developing Alzheimer’s disease. A recent study that looked at 396 studies has even been able to identify ten risk factors that are shown to increase the likelihood of developing the disease.

Here are the factors researchers identified – and why they’re associated with a higher risk.

1. Lower education level

A lower education level is associated with an increased risk of Alzheimer’s disease. Previous evidence shows the longer you spend in education, the lower your risk of developing dementia. Research looking at the brains of people from different ed…

Source: https://sharpbrains.com/blog/2020/07/27/systematic-review-finds-ten-lifestyle-factors-that-clearly-impact-the-probability-of-developing-alzheimers-disease-ad/

Although there’s still no cure, researchers are continuing to develop a better understanding of what increases a person’s risk of developing Alzheimer’s disease. A recent study that looked at 396 studies has even been able to identify ten risk factors that are shown to increase the likelihood of developing the disease.

Here are the factors researchers identified – and why they’re associated with a higher risk.

1. Lower education level

A lower education level is associated with an increased risk of Alzheimer’s disease. Previous evidence shows the longer you spend in education, the lower your risk of developing dementia. Research looking at the brains of people from different ed…

Dementia and Anger: Is Anger a Sign of Dementia?

Source https://feeds.feedblitz.com/~/631896230/0/griswoldhomecare~Dementia-and-Anger-Is-Anger-a-Sign-of-Dementia/

Image of senior woman yelling at a senior man

Caring for someone with dementia can be a challenging experience for everyone concerned. When a loved one begins to show signs of diminishing cognitive functions, family members may not understand the behaviors that accompany a diagnosis of dementia.
Dementia can’t be defined by one sign or symptom. The person with dementia may have trouble remembering, reasoning, and thinking. He or she may become more emotional than usual or display signs of depression or anger.
Dementia progresses in stages. You can review the common stages of dementia <a href="https://feeds.feedblitz.com/~/t/0/0/griswoldhomecare/~https://www.dementiacarecentral.com/aboutdementia/facts/sta…

Source https://feeds.feedblitz.com/~/631896230/0/griswoldhomecare~Dementia-and-Anger-Is-Anger-a-Sign-of-Dementia/

Image of senior woman yelling at a senior man

Caring for someone with dementia can be a challenging experience for everyone concerned. When a loved one begins to show signs of diminishing cognitive functions, family members may not understand the behaviors that accompany a diagnosis of dementia.
Dementia can’t be defined by one sign or symptom. The person with dementia may have trouble remembering, reasoning, and thinking. He or she may become more emotional than usual or display signs of depression or anger.
Dementia progresses in stages. You can review the common stages of dementia <a href="https://feeds.feedblitz.com/~/t/0/0/griswoldhomecare/~https://www.dementiacarecentral.com/aboutdementia/facts/sta…

Income and sugary beverage consumption

Source https://www.foodpolitics.com/2020/07/income-and-sugary-beverage-consumption/

A recent study confirms what we already knew: poorer people drink more sugary beverages than richer people.

This analysis suggests the richest 10% of families drink about 2.5 fewer sugary drinks a week than those in the poorest 10%.

These investigators found this relationship to hold up “even after taking into account things like education, race, gender, cognitive abilities and interest in nutrition.”

Drinking sugary beverages correlates with all those factors as well as with poor diets in general, overweight, the diseases for which overweight is a risk factor, and overall mortality.

I discu…

Source https://www.foodpolitics.com/2020/07/income-and-sugary-beverage-consumption/

A recent study confirms what we already knew: poorer people drink more sugary beverages than richer people.

This analysis suggests the richest 10% of families drink about 2.5 fewer sugary drinks a week than those in the poorest 10%.

These investigators found this relationship to hold up “even after taking into account things like education, race, gender, cognitive abilities and interest in nutrition.”

Drinking sugary beverages correlates with all those factors as well as with poor diets in general, overweight, the diseases for which overweight is a risk factor, and overall mortality.

I discu…

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