Cells communicate with one another constantly, and a large portion of that communication is not carried by individual secreted molecules, though there are certainly a lot of those, but rather takes the form of small membrane-bound packages of diverse molecules known as extracellular vesicles. Cells generate and secrete extracellular vesicles of various sizes, and other cells ingest them. Two important areas of active research into cell signaling are the way in which young tissue can restore the function of old cells, and the way in which senescent cells change the activity of surrounding cells for the worse. In both cases, extracellular vesicles are important in this process of communication and influence.
There is a substantial faction in the research community focused on potentially beneficial effects that derive from young blo…
Cells communicate with one another constantly, and a large portion of that communication is not carried by individual secreted molecules, though there are certainly a lot of those, but rather takes the form of small membrane-bound packages of diverse molecules known as extracellular vesicles. Cells generate and secrete extracellular vesicles of various sizes, and other cells ingest them. Two important areas of active research into cell signaling are the way in which young tissue can restore the function of old cells, and the way in which senescent cells change the activity of surrounding cells for the worse. In both cases, extracellular vesicles are important in this process of communication and influence.
There is a substantial faction in the research community focused on potentially beneficial effects that derive from young blo…
Today I’m releasing a training package called Fearless Purpose that is the culmination of the last few years of my life’s work.
The ebook & training system are about fearlessly training in the uncertainty and anxiety that gets in the way of doing our meaningful work.
It’s about cultivating depth in our purpose, mindfully working with the habitual patterns that hold us back, and practicing a courageous willingness to be with whatever fears, patterns, and resistance that arise for us.
It’s about the groundlessness of our uncertain lives, and how we f…
Today I’m releasing a training package called Fearless Purpose that is the culmination of the last few years of my life’s work.
The ebook & training system are about fearlessly training in the uncertainty and anxiety that gets in the way of doing our meaningful work.
It’s about cultivating depth in our purpose, mindfully working with the habitual patterns that hold us back, and practicing a courageous willingness to be with whatever fears, patterns, and resistance that arise for us.
It’s about the groundlessness of our uncertain lives, and how we f…
“Keep your attention focused entirely on what is truly your own concern, and be clear that what belongs to others is their business and none of yours.” ~Epictetus
Are you addicted to drama? I was, but I didn’t know it. I thought I was just responding to life, to what was happening. I really didn’t think I had a choice! The drama triangle is so pervasive, and can be so subtle, that it just seems normal. But it’s not, and there’s a much saner way to live, I found.
Dr. Stephen Karpman first described the drama triangle in the 1960’s.
“Keep your attention focused entirely on what is truly your own concern, and be clear that what belongs to others is their business and none of yours.” ~Epictetus
Are you addicted to drama? I was, but I didn’t know it. I thought I was just responding to life, to what was happening. I really didn’t think I had a choice! The drama triangle is so pervasive, and can be so subtle, that it just seems normal. But it’s not, and there’s a much saner way to live, I found.
Dr. Stephen Karpman first described the drama triangle in the 1960’s.
Here Matthew O’Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atherosclerosis and other conditions. Oxidized cholesterols, and largely 7-ketocholesterol, are the primary cause of dysfunction in the macrophage cells normally responsible for preventing the build up of fatty plaques in blood vessel walls. That dysfunction is the cause of atherosclerosis, and the fact that the presence of oxidized cholesterols increases with age is one of the reasons why atherosclerosis is an age-related d…
Here Matthew O’Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atherosclerosis and other conditions. Oxidized cholesterols, and largely 7-ketocholesterol, are the primary cause of dysfunction in the macrophage cells normally responsible for preventing the build up of fatty plaques in blood vessel walls. That dysfunction is the cause of atherosclerosis, and the fact that the presence of oxidized cholesterols increases with age is one of the reasons why atherosclerosis is an age-related d…
Have you ever tried mujadara? If not, you’re totally missing out.
What is Mujadara?
Mujadara is a satisfying vegetarian dish with Middle Eastern and Arab influences. It’s traditionally made with rice, lentils, and caramelized onions, making it incredibly affordable and satisfying.
The spices can range in simplicity from just salt, pepper, and cumin to more complex flavors like cinnamon, lemon peel, and cayenne peppe…
Have you ever tried mujadara? If not, you’re totally missing out.
What is Mujadara?
Mujadara is a satisfying vegetarian dish with Middle Eastern and Arab influences. It’s traditionally made with rice, lentils, and caramelized onions, making it incredibly affordable and satisfying.
The spices can range in simplicity from just salt, pepper, and cumin to more complex flavors like cinnamon, lemon peel, and cayenne peppe…
“You can’t stop the waves, but you can learn to surf.” ~Jon Kabat-Zinn
It happened in the middle of an intimate moment, about a month before my wedding.
One minute I was enjoying a kiss from my fiancé and the next thing I knew, I was clutching my face and writhing in agony.
At first, there was a loud thud in my chest, as if my heart had skipped a beat.
Then out of nowhere I started getting this strange sensation—like the kind of feeling you’d get on an elevator that’s going down too fast. The feeling was so disorienting I couldn’t help but let out a startled cry.
I felt what I would later describe as “the draining”—it was as if all the blood had poured out of my body in a split second and I was left with an icy, numb, and shaky s…
“You can’t stop the waves, but you can learn to surf.” ~Jon Kabat-Zinn
It happened in the middle of an intimate moment, about a month before my wedding.
One minute I was enjoying a kiss from my fiancé and the next thing I knew, I was clutching my face and writhing in agony.
At first, there was a loud thud in my chest, as if my heart had skipped a beat.
Then out of nowhere I started getting this strange sensation—like the kind of feeling you’d get on an elevator that’s going down too fast. The feeling was so disorienting I couldn’t help but let out a startled cry.
I felt what I would later describe as “the draining”—it was as if all the blood had poured out of my body in a split second and I was left with an icy, numb, and shaky s…
The philosophy of yoga is drawn from the vast teachings of the Vedas, the texts that describe the unity or “one-ness” that underlies the phenomenal world. Much of the Vedas are also concerned with “dharma”—the actions or conduct that allow us to be in harmony in all of our relationships, both externally with the world and those around us, as well as internally with ourselves.
Yoga provides specific practices for this purpose: yamas (social observances) and niyamas (personal observances). Yama and niyama are the first two of ashtanga yoga’s eight limbs. When combined with āsana (the practice of postures) and prāṇāyāma (breathing techniques), they help to bring the mind and senses into a state of stable attention. This allows for progression in the later four limbs of yoga, which focus on attaining high…
The philosophy of yoga is drawn from the vast teachings of the Vedas, the texts that describe the unity or “one-ness” that underlies the phenomenal world. Much of the Vedas are also concerned with “dharma”—the actions or conduct that allow us to be in harmony in all of our relationships, both externally with the world and those around us, as well as internally with ourselves.
Yoga provides specific practices for this purpose: yamas (social observances) and niyamas (personal observances). Yama and niyama are the first two of ashtanga yoga’s eight limbs. When combined with āsana (the practice of postures) and prāṇāyāma (breathing techniques), they help to bring the mind and senses into a state of stable attention. This allows for progression in the later four limbs of yoga, which focus on attaining high…
Objective: “The health impact of WGW [whole grain wheat] consumption was investigated by quantification of the body’s resilience, which was defined as the ‘ability to adapt to a standardized challenge.’”
Objective: “The health impact of WGW [whole grain wheat] consumption was investigated by quantification of the body’s resilience, which was defined as the ‘ability to adapt to a standardized challenge.’”
It is always pleasant to see new efforts to produce longevity-focused interest sites and publications; Longevity.Technology is a recent example, here publishing an interview with Aubrey de Grey of the SENS Research Foundation that touches on recent developments in the field of rejuvenation research. There have been many such news organization initiatives over the past ten to fifteen years, and all too few of them lasted. Hopefully that will change now that an industry of rejuvenation is forming, beginning with the development of senolytic therapies, and…
It is always pleasant to see new efforts to produce longevity-focused interest sites and publications; Longevity.Technology is a recent example, here publishing an interview with Aubrey de Grey of the SENS Research Foundation that touches on recent developments in the field of rejuvenation research. There have been many such news organization initiatives over the past ten to fifteen years, and all too few of them lasted. Hopefully that will change now that an industry of rejuvenation is forming, beginning with the development of senolytic therapies, and…
