It is never too late to start
Source https://seniorplanet.org/articles-open-thread-celebrity-age-gap/
Did you recognize more celebrities in the Oscars’ “In Memoriam” segment than during the awards? Welcome to the Celebrity Generation Gap.
The post Open Thread: Celebrity Generation Gap appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-open-thread-celebrity-age-gap/
Did you recognize more celebrities in the Oscars’ “In Memoriam” segment than during the awards? Welcome to the Celebrity Generation Gap.
The post Open Thread: Celebrity Generation Gap appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-realista-con-inteligencia-artificial/
La Inteligencia Artificial o “IA” ha dominado el mundo tecnológico; ahora Senior Planet avanza con nuevas clases de IA para adultos mayores. ¡Participe con nosotros!
The post Sea realista con respecto a la inteligencia artificial appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-realista-con-inteligencia-artificial/
La Inteligencia Artificial o “IA” ha dominado el mundo tecnológico; ahora Senior Planet avanza con nuevas clases de IA para adultos mayores. ¡Participe con nosotros!
The post Sea realista con respecto a la inteligencia artificial appeared first on Senior Planet from AARP.
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Source https://www.sonima.com/yoga/yoga-articles/sharath-tour-2024-2/
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The post Protected: Register Now: 2024 Classes With Sharath Jois in New York, Miami, and San Antonio appeared first on Sonima.
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Source https://www.sonima.com/yoga/yoga-articles/sharath-tour-2024-2/
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The post Protected: Register Now: 2024 Classes With Sharath Jois in New York, Miami, and San Antonio appeared first on Sonima.
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As some of you may know, I co-founded Repair Biotechnologies with Bill Cherman. The company is presently on the development of a gene therapy approach now demonstrated to rapidly reverse atherosclerosis in mice, the condition in which fatty plaques grow to narrow blood vessels and weaken blood vessel walls. One of the possible approaches to treating aging as a medical condition is to take the list of causes of human mortality, start at the top, and work down. Atherosclerosis is the single largest cause of death in our species, through the rupture of unstable atherosclerotic plaque leading to heart attack or stroke. The burden of established plaque …
As some of you may know, I co-founded Repair Biotechnologies with Bill Cherman. The company is presently on the development of a gene therapy approach now demonstrated to rapidly reverse atherosclerosis in mice, the condition in which fatty plaques grow to narrow blood vessels and weaken blood vessel walls. One of the possible approaches to treating aging as a medical condition is to take the list of causes of human mortality, start at the top, and work down. Atherosclerosis is the single largest cause of death in our species, through the rupture of unstable atherosclerotic plaque leading to heart attack or stroke. The burden of established plaque …
The balance of microbial populations making up the gut microbiome is different from individual to individual, and changes with age in detrimental ways. Pro-inflammatory microbes, as well as those that create otherwise harmful metabolites, expand in number at the expense of microbial populations that produce beneficial metabolites. Evidence strongly suggests that both variations between individuals and age-related changes in the gut microbiome can contribute to age-related disease and mortality. Here, for example, a study in rabbits shows that specific differences in the gut microbiome correlate well with obser…
The balance of microbial populations making up the gut microbiome is different from individual to individual, and changes with age in detrimental ways. Pro-inflammatory microbes, as well as those that create otherwise harmful metabolites, expand in number at the expense of microbial populations that produce beneficial metabolites. Evidence strongly suggests that both variations between individuals and age-related changes in the gut microbiome can contribute to age-related disease and mortality. Here, for example, a study in rabbits shows that specific differences in the gut microbiome correlate well with obser…
Source https://www.fightaging.org/archives/2024/04/mkp1-as-a-target-for-idiopathic-pulmonary-fibrosis/
The causes of idiopathic pulmonary fibrosis remain somewhat unclear, which is often the case for conditions in which treatments struggle to achieve more than a slowed progression. There is evidence for cellular senescence to drive the progression of fibrosis, but most research remains focused on the molecular biochemistry of fibroblasts, the cells responsible for building the collagen deposits characteristic of fibrotic tissue.
The process by which lung injury either leads to healing or fibrosis relies in part on what happens to a cell called a fibroblast, which forms connective tissue. Dur…
Source https://www.fightaging.org/archives/2024/04/mkp1-as-a-target-for-idiopathic-pulmonary-fibrosis/
The causes of idiopathic pulmonary fibrosis remain somewhat unclear, which is often the case for conditions in which treatments struggle to achieve more than a slowed progression. There is evidence for cellular senescence to drive the progression of fibrosis, but most research remains focused on the molecular biochemistry of fibroblasts, the cells responsible for building the collagen deposits characteristic of fibrotic tissue.
The process by which lung injury either leads to healing or fibrosis relies in part on what happens to a cell called a fibroblast, which forms connective tissue. Dur…
Source https://www.fightaging.org/archives/2024/04/bismonoacylglycerophosphates-accumulate-in-aged-tissues/
Lipid metabolism is changed and disrupted with advancing age, as is the case for all complex mechanisms in the body. There are a great many different lipids present in the body; even the list of classes of lipid is a long one. Finding specific changes that relate to aging can be interesting, but the challenge lie in better understanding how those changes come about, and whether they causes significant harm to tissues. Many age-related changes in molecular biochemistry are far downstream of the important causes of aging and do not cause much further disruption in and of themselves.
In recent years, laboratory research has shown that we may be able to counteract age-related diseases by intervening in the fundamental processes that lead to ageing. Although science has increasingly mapped out how metabolism changes during aging, large parts…
Source https://www.fightaging.org/archives/2024/04/bismonoacylglycerophosphates-accumulate-in-aged-tissues/
Lipid metabolism is changed and disrupted with advancing age, as is the case for all complex mechanisms in the body. There are a great many different lipids present in the body; even the list of classes of lipid is a long one. Finding specific changes that relate to aging can be interesting, but the challenge lie in better understanding how those changes come about, and whether they causes significant harm to tissues. Many age-related changes in molecular biochemistry are far downstream of the important causes of aging and do not cause much further disruption in and of themselves.
In recent years, laboratory research has shown that we may be able to counteract age-related diseases by intervening in the fundamental processes that lead to ageing. Although science has increasingly mapped out how metabolism changes during aging, large parts…
Source https://www.fightaging.org/archives/2024/04/parkinsons-disease-in-the-sens-view-of-damage-repair/
The Strategies for Engineered Negligible Senescence (SENS) is a view of aging as accumulated damage. Drawing from the extensive scientific literature on aging, the originators of SENS created an outline of the forms of cell and tissue damage that are fundamental causes of aging, in that they occur as a natural side-effect of the normal operation of our cellular biochemistry. So we might consider the loss of vital cells due to declining stem cell function, mutations to nuclear DNA and mitochondria…
Source https://www.fightaging.org/archives/2024/04/parkinsons-disease-in-the-sens-view-of-damage-repair/
The Strategies for Engineered Negligible Senescence (SENS) is a view of aging as accumulated damage. Drawing from the extensive scientific literature on aging, the originators of SENS created an outline of the forms of cell and tissue damage that are fundamental causes of aging, in that they occur as a natural side-effect of the normal operation of our cellular biochemistry. So we might consider the loss of vital cells due to declining stem cell function, mutations to nuclear DNA and mitochondria…
Source https://zenhabits.net/focus-of-a-monk/
As I write this, I’m on a long plane ride — I’ve written many posts on planes and trains, and I find it actually much easier to write this way despite the shakiness of my laptop on these rides.
It’s easy to write on planes and trains because there’s not as much to do. I don’t get the Internet option on planes because it really limits my options. That’s a good thing for focus.
On planes, I can do one of a few things: read, watch a movie, sleep, or write. Those are all good options, but they’re limited. I tend to think about it for a minute, and then choose one to focus on for a while.
At home and at work, however, our options are unlimited. And our brains seem to want to do it all, when we have unlimited options. We tend to jump from one thing to another, endlessly, until the sweet release of sleep takes us from all of our choices.
Monks hav…
Source https://zenhabits.net/focus-of-a-monk/
As I write this, I’m on a long plane ride — I’ve written many posts on planes and trains, and I find it actually much easier to write this way despite the shakiness of my laptop on these rides.
It’s easy to write on planes and trains because there’s not as much to do. I don’t get the Internet option on planes because it really limits my options. That’s a good thing for focus.
On planes, I can do one of a few things: read, watch a movie, sleep, or write. Those are all good options, but they’re limited. I tend to think about it for a minute, and then choose one to focus on for a while.
At home and at work, however, our options are unlimited. And our brains seem to want to do it all, when we have unlimited options. We tend to jump from one thing to another, endlessly, until the sweet release of sleep takes us from all of our choices.
Monks hav…
The consensus of the research community on senescent cells in old tissues is that (a) their presence causes harm, and (b) treatments based on the selective removal of such cells will be beneficial, reversing many aspects of aging and age-related disease. These cells secrete a pro-inflammatory mix of signal molecules that is disruptive to tissue structure and function when maintained over time. Cells become senescent constantly throughout life, only to be destroyed by programmed cell death or by the immune system. With advancing age, newly created senescent cells are cleared ever more slowly, however, and thus the burden of lingering senescent cells grows throughout the body.
As the authors of today’s open access paper note, the presence of senescent <a h…
The consensus of the research community on senescent cells in old tissues is that (a) their presence causes harm, and (b) treatments based on the selective removal of such cells will be beneficial, reversing many aspects of aging and age-related disease. These cells secrete a pro-inflammatory mix of signal molecules that is disruptive to tissue structure and function when maintained over time. Cells become senescent constantly throughout life, only to be destroyed by programmed cell death or by the immune system. With advancing age, newly created senescent cells are cleared ever more slowly, however, and thus the burden of lingering senescent cells grows throughout the body.
As the authors of today’s open access paper note, the presence of senescent <a h…