SIRT3 beneficially affects mitochondrial function, and its upregulation is a calorie restriction mimetic strategy, since it mediates some of the benefits resulting from a lowered calorie intake. Given this, there is some interest in this as a basis for treatments for neurodegenerative conditions, in which loss of mitochondrial function in the brain is thought to be an important contribution to pathology. Mitochondria are the power plants of the cell, and the brain requires a great deal of energy to operate. So far, efforts to improve mitochondrial function in aged tissues by targeting the expressed levels of specific proteins or <a href="https://en.wikipedia.org/wiki/Metabolite…
SIRT3 beneficially affects mitochondrial function, and its upregulation is a calorie restriction mimetic strategy, since it mediates some of the benefits resulting from a lowered calorie intake. Given this, there is some interest in this as a basis for treatments for neurodegenerative conditions, in which loss of mitochondrial function in the brain is thought to be an important contribution to pathology. Mitochondria are the power plants of the cell, and the brain requires a great deal of energy to operate. So far, efforts to improve mitochondrial function in aged tissues by targeting the expressed levels of specific proteins or <a href="https://en.wikipedia.org/wiki/Metabolite…
“The truth is that the way other people see us isn’t about us—it’s about them and their own struggles, insecurities, and limitations. You don’t have to allow their judgment to become your truth.” ~Daniell Koepke
As a child growing up with a highly sensitive mom, I often noticed her go quiet at the dinner table after my stepfather would make some little comment. Looking back, I know he was just tired and a bit grouchy from a long day at work, but my mom felt hurt by his words.
Over the years, the comments didn’t lessen, but I noticed my mother being less and less bothered by them. They seemed to slide off of her like water off a duck’s back. As a result, my parents seemed to have a lot more fun, laughter, and ease together—and still, forty som…
“The truth is that the way other people see us isn’t about us—it’s about them and their own struggles, insecurities, and limitations. You don’t have to allow their judgment to become your truth.” ~Daniell Koepke
As a child growing up with a highly sensitive mom, I often noticed her go quiet at the dinner table after my stepfather would make some little comment. Looking back, I know he was just tired and a bit grouchy from a long day at work, but my mom felt hurt by his words.
Over the years, the comments didn’t lessen, but I noticed my mother being less and less bothered by them. They seemed to slide off of her like water off a duck’s back. As a result, my parents seemed to have a lot more fun, laughter, and ease together—and still, forty som…
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit: https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Aging as a Disease: a Zoo Contains Animals, But is Not Itself an Animal
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit: https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Aging as a Disease: a Zoo Contains Animals, But is Not Itself an Animal
Life is busy and sometimes a trip the supermarket just doesn’t fit in. Luckily, there’s a slew of produce subscription boxes that can be shipped directly to your door, so you don’t even have to go outside.
Similar to a CSA (community-supported agriculture), which connects consumers with local farmers, these subscription services offer the same kind of service — but instead of requiring you to visit drop-off locations to snag your weekly bounty, produce boxes are sent directly to your home.
(Of course, if you want to supplement your produce boxes with a visit to your local farmer’s market or even a grocery store, that’s definitely an option too.)
Life is busy and sometimes a trip the supermarket just doesn’t fit in. Luckily, there’s a slew of produce subscription boxes that can be shipped directly to your door, so you don’t even have to go outside.
Similar to a CSA (community-supported agriculture), which connects consumers with local farmers, these subscription services offer the same kind of service — but instead of requiring you to visit drop-off locations to snag your weekly bounty, produce boxes are sent directly to your home.
(Of course, if you want to supplement your produce boxes with a visit to your local farmer’s market or even a grocery store, that’s definitely an option too.)
Study data here shows that age-related enlargement of perivascular spaces in the brain is to some degree driven by raised blood pressure, and reversible given control of blood pressure. As the researchers note, this enlargement is a part of the issues that lead to a reduced clearance of metabolic waste from the brain in later life. This reduced clearance is likely an important factor in the development of neurodegenerative conditions. All told, the raised blood pressure of hypertension is one of the more important ways in which deeper causes of aging are converted to tissue dysfunction and outright structural damage throughout the body. Even without addressing the underlying causes, forcing a reduction in blood pressure via <a href="https://en….
Study data here shows that age-related enlargement of perivascular spaces in the brain is to some degree driven by raised blood pressure, and reversible given control of blood pressure. As the researchers note, this enlargement is a part of the issues that lead to a reduced clearance of metabolic waste from the brain in later life. This reduced clearance is likely an important factor in the development of neurodegenerative conditions. All told, the raised blood pressure of hypertension is one of the more important ways in which deeper causes of aging are converted to tissue dysfunction and outright structural damage throughout the body. Even without addressing the underlying causes, forcing a reduction in blood pressure via <a href="https://en….
Traditionally, potato salad is a staple of summer — but in my mind, it’s a treasure to be enjoyed year-round.
Maybe it’s because, in my house, the favorite potato salad is a Japanese version whose perfect balance of creaminess, tartness, and even sweetness is so delicious, I often eat it on its own, without any meaty or grilled companions.
One of the best recipes for Japanese potato salad comes from Shirley Karasawa of the now-defunct blog, Lovely Lanvin (lucky for us, she’s still very active on Instagram).
Traditionally, potato salad is a staple of summer — but in my mind, it’s a treasure to be enjoyed year-round.
Maybe it’s because, in my house, the favorite potato salad is a Japanese version whose perfect balance of creaminess, tartness, and even sweetness is so delicious, I often eat it on its own, without any meaty or grilled companions.
One of the best recipes for Japanese potato salad comes from Shirley Karasawa of the now-defunct blog, Lovely Lanvin (lucky for us, she’s still very active on Instagram).
Are IBS symptoms like gas and bloating stopping you from getting busy? Taking steps to manage IBS and being honest with your partner can help get you back in the mood.
Picture it: You and your partner are fooling around when you experience a gas attack or feel a sudden urge to use the bathroom.
If you’re living with irritable bowel syndrome (IBS), symptoms such as bloating, gas, and abdominal pain can really kill the mood.
But it’s still possible to have a healthy and enjoyable sex life, whether you’re in a committed relationship or playing the field.
Here’s the 411 on how IBS can affect dating and sex and what you can do to bring your sexy back.
The challenges of dating and intimacy if you have IBS
Are IBS symptoms like gas and bloating stopping you from getting busy? Taking steps to manage IBS and being honest with your partner can help get you back in the mood.
Picture it: You and your partner are fooling around when you experience a gas attack or feel a sudden urge to use the bathroom.
If you’re living with irritable bowel syndrome (IBS), symptoms such as bloating, gas, and abdominal pain can really kill the mood.
But it’s still possible to have a healthy and enjoyable sex life, whether you’re in a committed relationship or playing the field.
Here’s the 411 on how IBS can affect dating and sex and what you can do to bring your sexy back.
The challenges of dating and intimacy if you have IBS
